Class 2 Biosafety Cabinets – Vital for Lab Safety and Biological Containment
Maintaining a safe lab environment is crucial in today’s advanced research and clinical setups. Whether it's biotech development, pharmaceutical research, or microbiological analysis, biosafety cabinets play an integral role in contamination prevention and sample integrity.
Of all types, Class 2 cabinets are most commonly used due to their efficiency and versatility. These units are essential for labs working with infectious materials or clinical diagnostics.
Biosafety Cabinets – How They Work and Why They Matter
Biosafety cabinets are specially designed, enclosed systems that ventilate and filter lab air. They use high-efficiency filters to purify air entering and leaving the cabinet.
These units are generally classified into three main types: Class I, II, and III based on containment level. Among these, Class 2 cabinets are the most versatile and commonly used.
What Are Class 2 Biosafety Cabinets?
Class 2 Biosafety Cabinets ensure safety on all fronts—personnel, workspace, and biological material. They direct filtered airflow in a laminar pattern over the work surface.
Contaminated air is drawn into the cabinet and filtered through HEPA systems before recirculation or exhaust. These cabinets are suited for clinical, research, and pharmaceutical lab applications.
Key Features of Microbiological Safety Cabinets
A Class 2 microbiological safety cabinet includes several critical technologies such as:
• HEPA/ULPA filtration to trap microbes and particles
• Uniform downward airflow to protect the sample zone
• Inward airflow to keep aerosols contained
• Built-in UV sterilisation for decontaminating Biosafety Cabinets surfaces
• Noise-reducing construction for better working conditions
• Front glass for full control and protection
These elements create a clean, contained, and user-friendly workspace.
Industries and Labs That Rely on Microbiological Safety Cabinets
Class 2 Biosafety Cabinets are commonly used across microbiology, biotechnology, diagnostics, and pharma. They are critical for DNA/RNA extraction, pathogen culture, and molecular assays.
From universities to private pathology labs, Class 2 cabinets ensure lab hygiene and sample integrity.
Why Laboratories Prefer Class II Safety Cabinets
Using Class 2 cabinets offers multiple advantages including operator protection and experimental reliability:
• Reduces the risk of sample cross-contamination and error
• Acts as a barrier between user and biohazard
• Minimises lab contamination and pollution risks
These cabinets support biosafety goals while improving lab productivity.
Design and Compliance Standards
Top manufacturers ensure their cabinets meet certifications like NSF 49, EN 12469, and WHO recommendations. Class 2 units are sub-classified as A1, A2, B1, and B2—based on varying airflow balance and ducting needs.
• Type A2: Recirculates 70% and exhausts 30% of filtered air
• Type B2: Used for hazardous vapors and chemicals
Selecting the right configuration ensures compliance and safety.
Tips for Purchasing the Ideal Biosafety Cabinet
Before purchasing, consider:
• The types of agents and materials handled
• Ventilation compatibility and placement
• Operational costs and technical support options
• Service network and part availability
Partnering with a trusted provider helps meet both performance and safety needs.
Best Practices for Using Class II Biosafety Cabinets
For optimal results:
• Avoid placing near doors, vents, or fans
• Ensure annual certification and airflow testing
• Ensure operators follow best practices
Operational best practices include:
• Use gloves, gowns, and face shields while operating
• Minimise hand movements inside the cabinet
• Decontaminate surfaces before and after use
• Never activate UV when humans are present
Why Class 2 Cabinets Are a Must-Have in Labs
Class 2 biosafety cabinets are a cornerstone of any safe, efficient laboratory. They safeguard both research outcomes and operator health.
From pathology labs to advanced genetic testing, Class II cabinets support world-class laboratory practices. When investing in a biosafety cabinet, choose performance and reliability over cost-cutting—because safe science starts with smart containment.